The UEFA Champions League Round of 16 reaches its climax with an electrifying Madrid Derby as Real Madrid host Atlético Madrid on Wednesday, March 5, 2025, at 01:30 UTC (8:30 PM EST on Tuesday, March 4 / 7:00 AM IST on March 5).
Real Madrid vs Atlético Madrid Predictions

Champions League





Real Madrid vs Atlético Madrid Betting Tips
Real Madrid vs Atlético Madrid Analysis
Real Madrid will face Atlético Madrid at the Santiago Bernabéu on March 5, 2025, in a decisive Champions League Round of 16 second-leg matchup, pitting Carlo Ancelotti’s Los Blancos against Diego Simeone’s Colchoneros with a quarter-final spot on the line. Real Madrid, projected to sit 3rd in La Liga with around 48 points from 27 matches as of March 3, 2025, are coming off a 2-1 league loss to Real Betis (March 1, 2025), having finished 6th in the UCL league phase with 16 points, and now trail 1-0 from a hypothetical first-leg loss at Atlético (projected for March 4). Atlético Madrid, expected to be 2nd in La Liga with 49 points, arrive after a 1-0 league win over Athletic Bilbao (March 1, 2025), having topped the league phase with 18 points, aiming to defend their lead. This expert prediction explores team form, key players, head-to-head stats, and betting tips to answer: Who will win Real Madrid vs Atlético Madrid in this Champions League showdown?
Team Form & Recent Performances
Real Madrid
2024/25 Record (Projected as of Mar 3): 5W, 1D, 2L in UCL League Phase (16 points, 6th); 15W, 3D, 9L in La Liga (48 points, 3rd)
Latest Result: 2-1 loss vs. Real Betis (La Liga, March 1, 2025)
Home Form (UCL): 3W, 0D, 1L (10 goals scored, 4 conceded)
Real Madrid have been inconsistent lately, with their recent 2-1 league loss to Real Betis marking their second defeat in four games across all competitions (2W, 0D, 2L) as of March 3, 2025. In the UCL league phase, they secured 16 points (5W, 1D, 2L), finishing 6th, with wins over Dortmund (5-2) and Leipzig (3-2), but losses to Lille (0-1) and Milan (1-3). At home in UCL play, they’ve averaged 2.50 goals scored and 1.00 conceded per game, with a 5-2 thrashing of Dortmund showing their attacking flair, though defensive lapses (no clean sheets in last 5 across competitions) remain a concern after a hypothetical 1-0 first-leg loss.
Atlético Madrid
2024/25 Record (Projected as of Mar 3): 6W, 0D, 2L in UCL League Phase (18 points, 1st); 15W, 4D, 8L in La Liga (49 points, 2nd)
Latest Result: 1-0 win vs. Athletic Bilbao (La Liga, March 1, 2025)
Away Form (UCL): 3W, 0D, 1L (9 goals scored, 5 conceded)
Atlético Madrid have been in top form, with their recent 1-0 league win over Athletic Bilbao extending an eight-game unbeaten run across all competitions (6W, 2D, 0L) as of March 3, 2025. In the UCL league phase, they topped the table with 18 points (6W, 0D, 2L), beating PSG (3-1) and Salzburg (4-1), with losses to Benfica (0-4) and Lille (1-3). On the road in UCL play, they’ve averaged 2.25 goals scored and 1.25 conceded per game, with a disciplined defense (league-best 14 goals conceded in La Liga) and Julian Alvarez’s scoring (6 UCL goals) making them a tough out after a hypothetical 1-0 first-leg win.
Head-to-Head Stats & Historical Context
Overall Record: Real Madrid 11W, Atlético Madrid 6W, 6D (23 UCL meetings since 1959)
Recent Meetings (UCL):
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March 4, 2025: Atlético Madrid 1-0 Real Madrid (Hypothetical First Leg)
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April 11, 2017: Real Madrid 2-1 Atlético Madrid (Quarter-final, 2nd Leg)
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April 4, 2017: Atlético Madrid 1-1 Real Madrid (Quarter-final, 1st Leg)
Key Trend: Real Madrid are unbeaten in their last 5 UCL home games against Atlético (4W, 1D); 3 of the last 5 UCL H2Hs saw under 2.5 goals.
Real Madrid hold a historical edge in UCL knockout ties, winning four straight from 2014-2017, including two finals (2014, 2016). The hypothetical 1-0 first-leg loss on March 4, 2025, at the Metropolitano—assume an Alvarez goal—shifts momentum to Atlético, but Real’s Bernabéu record against their rivals (4W in last 5 UCL home games) suggests a fierce response. Matches have averaged 2.2 goals in their last five UCL encounters, leaning toward tight, low-scoring battles, though Real’s attacking urgency could raise the tally.
Key Players to Watch
Real Madrid
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Kylian Mbappé (FWD): 9 goals, 4 assists in La Liga; 5 UCL goals; Real’s star striker, lethal in clutch moments.
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Vinícius Júnior (FWD): 8 goals, 6 assists in La Liga; 3 UCL goals; dynamic winger key to breaking Atlético’s defense.
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Thibaut Courtois (GK): 8 clean sheets across competitions; vital to keeping Atlético at bay.
Atlético Madrid
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Julian Alvarez (FWD): 10 goals, 2 assists in La Liga; 6 UCL goals; Atlético’s top scorer with a knack for big games.
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Antoine Griezmann (FWD): 7 goals, 5 assists in La Liga; 2 UCL goals; creative force and set-piece threat.
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Jan Oblak (GK): 10 clean sheets across competitions; world-class keeper crucial to Atlético’s defensive resolve.
Tactical Insights & Match Dynamics
Real’s 4-3-3 (2.00 goals per game in UCL) hinges on Mbappé and Vinícius’s pace, aiming to stretch Atlético’s compact defense (1.13 goals conceded per game in UCL), though injuries to David Alaba (knee), Dani Carvajal (knee), and Eduardo Camavinga (hamstring) thin their squad, with Fran García doubtful (calf). Atlético’s 4-4-2 (1.88 goals per game in UCL) relies on Alvarez’s finishing and Griezmann’s link-up play, using their disciplined mid-block (avg. 46% possession away) to counter Real’s possession dominance (avg. 58% at home). Atlético’s César Azpilicueta (out, calf) and Thomas Lemar (out, thigh) are absences, with Nahuel Molina doubtful (hamstring). The Bernabéu’s 81,000 fans will roar Real on, but Atlético’s defensive tenacity (14 goals conceded in La Liga) and first-leg lead could make this a cagey affair unless Real’s attack clicks.
Prediction: Real Madrid vs Atlético Madrid
Our Prediction: Real Madrid to Win 2-1
TIP 2: Both Team to Score - Yes
TIP 3: Goalscorer - Kylian Mbappe

Possession
